How to Perform a RMP Frequency Calcuation

This guide walks you through performing a Mixture Frequency Calculation Page.  It is used to perform frequency calculations on a two or three-person mixture sample.

Select the Mixture Sample 

To obtain the RMP Calculation page, click on the RMP button.  The Select/Pick via mouse window will appear.  Select the sample you wish to perform the calculations on with your mouse or click on the ▼arrow and select from the drop down list.

The RMP page will display.

All Loci and their corresponding alleles are imported into the page.

On the left half of the screen is each locus with each corresponding allele(s) with the calculations for each allele by ethnicity.

On the right half of the screen, you can see the calculation of any allele combination.

Add Mixture Combinations

At the first allele, hit the arrow next to “Add Combo” box to bring down the available allele combination drop down list.

Select the appropriate combination and ArmedXpert will automatically fill in the calculations for that allele combination.  The drop down list gives you all possible combinations as well as RMP (Random Match Probability) and ‘2p’ options, as well as a remove locus option and add comment option.

If a RMP or ‘2p’ option is chosen, no other combinations can be added for that Locus.  

If you choose the remove locus option, it removes the locus calculation from this page only.  The locus still remains on the sample table. 

 To add a locus that was deleted back, double click the locus name.

When completed, the “Add Combo” box will appear in the next column.

Add all combinations that are necessary to perform the calculation.  Continue this process for each locus listed.

Remove a Combination

To remove a combination, place your mouse over the combination.  The combination will appear gray and will have a red line through it.  

Double click on the box and it will be removed.  

It can be added back at any time. 

Mathematical Calculations Shown

When either one of the RMP combos or the ‘2p’ combos are chosen, the math used will appear in blue next to the combo when you have your mouse over the combo.  Click on any of the + left of the ethnicity and the math for that type will be shown.

You can also see the math calculations for all combinations, by clicking on the calculations tab on the bottom of the page.

Automatically Add a Sample

Go the bottom of the window, either click on the Pick via mouse button and select your reference or click on the ▼arrow and select the sample from the drop down list of samples. This will automatically fill in the allele combinations for that sample and all calculations will be done automatically

Mixture Calculations Shown

 The calculation for the each ethnicity for the entire profile is located at the bottom of the page.  The calculations are shown in both exponential and alphanumeric form.

It also displays on the bottom of the page, the theta value used as well as the number of contributors.